Solid solution beadlet
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United States of America Patent
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-
Feb 17, 2004
Grant Date -
Jul 5, 2001
app pub date -
Sep 18, 1998
filing date -
Sep 19, 1997
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Disclosed is a beadlet comprising (i) a hydrophobic long chain fatty acid or ester material; (ii) a surfactant; and (iii) a therapeutic agent which in admixture form a solid solution at room temperature. The hydrophobic material preferably has a melting point of about 40 to about 100.degree. C., and is most preferably glyceryl behenate. The surfactant is preferably a polyglycolyzed glyceride, polyoxyethylene sorbate, ethylene or propylene block copolymer or combinations thereof, and is most preferably polyoxyethylene 20 sorbitan monolaurate.
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