Pulmonary delivery of active agents
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United States of America Patent
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Feb 17, 2004
Grant Date -
Apr 17, 2003
app pub date -
Jun 14, 2002
filing date -
Jul 27, 1998
priority date (Note) -
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status (Latency Note)
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Abstract
The present invention provides methods for administering an active agent to an animal in need of the agent by the pulmonary route. This method comprises administering via the pulmonary route, a composition comprising (a) an active agent and (b)(i) an acylated amino acid, (ii) a sulfonated amino acid, or (iii) a combination of (i) and (ii). Administration of the compositions of the present invention provide improved pulmonary delivery and greater bioavailability of the active agent than administration of the active agent alone. As a result, lesser amounts of the active agent may be administered to obtain a desired result when contained in the composition of the present invention than when administered alone.
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