Combination drug therapy for glycolipid storage diseases
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United States of America Patent
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Feb 24, 2004
Grant Date -
Sep 12, 2002
app pub date -
Jan 22, 2002
filing date -
Jul 26, 1999
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Abstract
A combination drug therapy is disclosed for the treatment of a patient affected with Gaucher's disease or other such glycolipid storage diseases. The method comprises administering to said patient a therapeutically effective amount of both a N-alkyl derivative of deoxynojirimycin (DNJ) and a glucocerebrosidase enzyme to alleviate or inhibit the glycolipid storage disease. The alkyl group has from about two to about 20 carbon atoms and preferably is butyl, nonyl or decyl.
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