Cytoplasmic gene inhibition or gene expression in transfected plants by a tobraviral vector
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United States of America Patent
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Mar 2, 2004
Grant Date -
Nov 7, 2002
app pub date -
Jan 25, 2001
filing date -
Jan 16, 1998
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Expired
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Abstract
This invention is directed to a monopartite RNA viral vector comprising modified tobravirus RNA-1 comprising an inserted foreign RNA sequence. This invention is also directed to a bipartite RNA viral vector derived from a tobravirus, wherein the vector comprises one or more foreign RNA sequences. The invention is directed to a method of silencing one or more endogenous plant host genes and a method of simultaneously silencing a plant host gene and expressing a foreign gene in a plant host. Such methods comprise infecting a plant host with a bipartite vector comprising modified tobravirus RNA-1 and RNA-2.
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