Process for selective derivatization of taxanes

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United States of America Patent

PATENT NO 6706896
SERIAL NO

09672270

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Abstract

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Processes for the preparation of taxol and other taxanes through selective derivatization of the C(7) and C(10) hydroxyl groups of 10-DAB, particularly a novel process using a new strategy in which the C(10) hydroxyl group is protected or derivatized prior to the C(7) hydroxyl group; and the provision of C(7) and C(10) derivatized 10-DAB compounds.

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Patent Owner(s)

Patent OwnerAddress
FLORIDA STATE UNIVERSITY2035 EAST PAUL DIRAC DRIVE 109 HERB MORGAN BUILDING TALLAHASSEE FL 32310 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clarke, Paul A Tallahassee, FL 11 137
Holton, Robert A Tallahassee, FL 134 2437
Zhang, Zhuming Montclair, NJ 58 543

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