Brain fluid ion concentration modification for treating neurological disorders
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United States of America Patent
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Mar 23, 2004
Grant Date -
Oct 31, 2002
app pub date -
Jun 18, 2002
filing date -
Apr 28, 2000
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Abstract
Epilepsy and other neurological disorders that are affected by the electrical potential difference between intracellular fluid and extra-cellular fluid and therefore the cell membrane potentials, and therefore the thresholds for the communication between brain cells can be controlled by re-circulating extra-cellular brain fluid after the fluid has been treated to alter its ion concentrations. A computer-controlled pump can precisely control the extraction and delivery of brain fluid after the ion concentration of the fluid is appropriately adjusted, e.g. guided by the Goldmann equation. Well-known techniques for modifying ion concentrations can be used to raise or lower ion concentrations as needed.
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