Stent treatment apparatus and method

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United States of America Patent

PATENT NO 6709449
APP PUB NO 20020138126A1
SERIAL NO

09759906

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Manual stent manipulation before implantation results in foreign body contamination and increased neointimal hyperplasia. Rinsing commercially available sterile stents with high pressure immediately before implantation eliminates residual surface stent contaminants and reduces inflammation elicited by stent struts. Ex-vivo stent expansion and surface analysis revealed that rinsed stents had fewer surface contaminants than untouched or handled stents. In a porcine stent restenosis model, rinsed stents elicited less inflammation and less neointimal hyperplasia at one month than handled and untouched stents. Pressure-rinsing of coronary stents immediately before implantation reduces inflammation and neointimal hyperplasia.

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Patent Owner(s)

Patent OwnerAddress
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH200 FIRST STREET SW ROCHESTER MN 55905

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bayes-Genis, Atoni Barcelona, ES 1 33
Camrud, Allan R Rochester, MN 5 481
Schwartz, Robert S Rochester, MN 221 16235

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