US Patent No: 6,713,119

Number of patents in Portfolio can not be more than 2000

Biocompatible coating for a prosthesis and a method of forming the same

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A coating for a prosthesis, for example a stent, and a composition for forming the coating is disclosed. The coating can serve as a primer, allowing substances, such as polymers, to be effectively secured by the prosthesis. Alternatively, the coating can serve as a reservoir, allowing for the local and sustained release of a therapeutic substance to biological tissues. The composition can be formed from an ethylene vinyl alcohol copolymer and a dimethylsulfoxide solvent, with or without a therapeutic substance. Alternatively, the composition can be formed from an ethylene vinyl alcohol copolymer, a dimethylsulfoxide solvent, and a wetting fluid, with or without a therapeutic substance. The composition is applied to a surface of the prosthesis and essentially all of the dimethylsulfoxide solvent or dimethylsulfoxide solvent/wetting fluid is removed or allowed to evaporate to form the coating.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ADVANCED CARDIOVASCULAR SYSTEMS, INC.SANTA CLARA, CA1400

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Castro, Daniel A Santa Clara, CA 12 335
Guruwaiya, Judy A San Jose, CA 22 2917
Harish, Sameer Fremont, CA 13 2655
Hossainy, Syed F A Fremont, CA 214 9655
Sanders-Millare, Deborra San Jose, CA 13 2242
Wu, Steven Z Santa Clara, CA 18 3429

Cited Art Landscape

Patent Info (Count) # Cites Year
 
LIFEPORT SCIENCES LLC (1)
6,165,212 Expandable supportive endoluminal grafts 449 1999
 
Other [Check patent profile for assignment information] (1)
5,980,928 Implant for preventing conjunctivitis in cattle 391 1997
 
MINNESOTA MINING AND MANUFACTURING COMPANY (1)
* 4,977,901 Article having non-crosslinked crystallized polymer coatings 389 1990
 
CORDIS CORPORATION (1)
6,153,252 Process for coating stents 722 1999
 
Advanced Cardiovascular Systems, Inc. (2)
5,605,696 Drug loaded polymeric material and method of manufacture 679 1995
5,700,286 Polymer film for wrapping a stent structure 681 1996
 
MICRO THERAPEUTICS, INC. (4)
5,667,767 Compositions for use in embolizing blood vessels 501 1995
5,830,178 Methods for embolizing vascular sites with an emboilizing composition comprising dimethylsulfoxide 496 1996
5,851,508 Compositions for use in embolizing blood vessels 429 1997
6,015,541 Radioactive embolizing compositions 431 1997
 
GENZYME CORPORATION (1)
5,328,471 Method and apparatus for treatment of focal disease in hollow tubular organs and other tissue lumens 562 1993
 
LATHAM, DANIEL W. (1)
5,464,650 Intravascular stent and method 872 1993
 
TERUMO KABUSHIKI KAISHA (1)
5,670,558 Medical instruments that exhibit surface lubricity when wetted 412 1995
 
Rochester Medical Corporation, a subsidiary of C.R. Bard, Inc. (1)
5,971,954 Method of making catheter 387 1997
 
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (1)
5,578,073 Thromboresistant surface treatment for biomaterials 383 1994
 
VENTION MEDICAL ADVANCED COMPONENTS, INC. (2)
5,628,730 Phoretic balloon catheter with hydrogel coating 390 1994
5,800,392 Microporous catheter 283 1996
 
MEDTRONIC, INC. (2)
4,886,062 Intravascular radially expandable stent and method of implant 1409 1987
5,865,814 Blood contacting medical device and method 450 1997
 
ANGIOTECH BIOCOATINGS CORP. (1)
5,716,981 Anti-angiogenic compositions and methods of use 781 1995
 
EXPANDABLE GRAFTS PARTNERSHIP, 8000 I.H. 10 WEST, STE. 1265, SAN ANTONIO, TX A GENERAL PARTNERSHIP OF TX. (1)
4,733,665 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft 2496 1985
 
COOK INCORPORATED (1)
4,800,882 Endovascular stent and delivery system 1341 1987
 
BOSTON SCIENTIFIC TECHNOLOGY, INC. (1)
6,010,530 Self-expanding endoluminal prosthesis 359 1998
 
MED INSTITUTE, INC. (3)
6,096,070 Coated implantable medical device 905 1996
5,824,049 Coated implantable medical device 866 1996
5,873,904 Silver implantable medical device 849 1997
 
BOSTON SCIENTIFIC SCIMED, INC. (3)
5,837,313 Drug release stent coating process 746 1996
5,980,972 Method of applying drug-release coatings 513 1997
6,258,121 Stent coating 457 1999
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (9)
* 2003/0072,868 Methods of forming a coating for a prosthesis 152 2002
* 2004/0182,312 Apparatus and method for coating implantable devices 10 2004
* 2004/0187,775 Coupling device for a stent support fixture 2 2004
* 2005/0100,609 Phase-separated polymer coatings 48 2004
* 2006/0216,324 Composition and method for preparing biocompatible surfaces 13 2006
* 2007/0053,953 Method of loading beneficial agent to a prosthesis by fluid-jet application 3 2006
* 2009/0012,606 BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS 1 2008
* 2009/0012,259 BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS 0 2008
* 2009/0163,995 EXPANDABLE MEDICAL DEVICE FOR DELIVERY OF BENEFICIAL AGENT 17 2009
 
OrbusNeich Medical, Inc. (1)
8,088,060 Progenitor endothelial cell capturing with a drug eluting implantable medical device 3 2006
 
Abbott Cardiovascular Systems Inc. (49)
8,778,014 Coatings for preventing balloon damage to polymer coated stents 1 2004
8,586,069 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders 1 2005
* 2006/0105,019 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders 7 2005
* 2007/0196,428 Nitric oxide generating medical devices 13 2006
7,985,441 Purification of polymers for coating applications 8 2006
8,603,530 Nanoshell therapy 0 2006
8,048,448 Nanoshells for drug delivery 2 2006
8,017,237 Nanoshells on polymers 3 2006
* 2007/0198,080 Coatings including an antioxidant 24 2006
7,569,655 Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same 5 2007
8,029,816 Medical device coated with a coating containing elastin pentapeptide VGVPG 17 2007
* 2008/0038,310 Coating comprising an elastin-based copolymer 3 2007
8,147,769 Stent and delivery system with reduced chemical degradation 2 2007
9,056,155 Coatings having an elastic primer layer 0 2007
8,109,904 Drug delivery medical devices 4 2007
8,048,441 Nanobead releasing medical devices 4 2007
8,703,169 Implantable device having a coating comprising carrageenan and a biostable polymer 1 2007
8,007,857 Methods for controlling the release rate and improving the mechanical properties of a stent coating 1 2007
8,673,334 Stent coatings comprising hydrophilic additives 1 2007
7,749,263 Poly(ester amide) filler blends for modulation of coating properties 0 2008
8,118,863 RGD peptide attached to bioabsorbable stents 0 2008
8,062,350 RGD peptide attached to bioabsorbable stents 0 2008
8,435,550 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 1 2008
8,226,603 Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery 2 2008
8,049,061 Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery 4 2008
* 2010/0076,401 Expandable Member Having A Covering Formed Of A Fibrous Matrix For Intraluminal Drug Delivery 13 2008
8,076,529 Expandable member formed of a fibrous matrix for intraluminal drug delivery 1 2008
* 2010/0081,992 Expandable Member Formed Of A Fibrous Matrix For Intraluminal Drug Delivery 24 2008
8,603,634 End-capped poly(ester amide) copolymers 0 2009
* 2009/0232,865 End-Capped Poly(Ester Amide) Copolymers 0 2009
8,183,337 Method of purifying ethylene vinyl alcohol copolymers for use with implantable medical devices 0 2009
* 2010/0285,085 BALLOON COATING WITH DRUG TRANSFER CONTROL VIA COATING THICKNESS 33 2009
8,389,041 Systems and methods for rotating and coating an implantable device 1 2010
8,647,655 Biocompatible polyacrylate compositions for medical applications 0 2010
8,709,469 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 0 2010
8,871,883 Biocompatible coating for implantable medical devices 0 2010
8,500,687 Stent delivery system having a fibrous matrix covering with improved stent retention 0 2011
* 8,616,152 Stent coating apparatus 0 2012
8,592,036 Nanoshells on polymers 0 2012
8,758,801 Coatings for implantable devices comprising poly(hydroxy-alkanoates) and diacid linkages 0 2012
8,586,075 Coatings for implantable devices comprising poly(hydroxy-alkanoates) and diacid linkages 0 2012
8,632,841 Systems and methods for rotating and coating an implantable device 0 2013
8,808,342 Nanoshell therapy 0 2013
8,986,726 Biocompatible polyacrylate compositions for medical applications 0 2013
8,871,236 Biocompatible polyacrylate compositions for medical applications 0 2013
RE45744 Temperature controlled crimping 0 2013
9,067,000 End-capped poly(ester amide) copolymers 0 2013
9,138,337 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 0 2014
9,101,697 Hyaluronic acid based copolymers 0 2014
 
Endovascular Devices, Inc. (1)
* 2008/0161,908 Apparatus and Method for Delivery of Mitomycin Through an Eluting Biocompatible Implantable Medical Device 0 2008
 
Advanced Cardiovascular Systems, Inc. (182)
7,682,669 Methods for covalently immobilizing anti-thrombogenic material into a coating on a medical device 1 2001
8,303,651 Polymeric coating for reducing the rate of release of a therapeutic substance from a stent 1 2001
* 2007/0032,853 40-O-(2-hydroxy)ethyl-rapamycin coated stent 11 2002
8,506,617 Micronized peptide coated stent 1 2002
7,217,426 Coatings containing polycationic peptides for cardiovascular therapy 40 2002
7,070,798 Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine 22 2002
7,056,523 Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine 12 2002
7,033,602 Polycationic peptide coatings and methods of coating implantable medical devices 18 2002
7,011,842 Polycationic peptide coatings and methods of making the same 10 2002
6,994,867 Biocompatible carrier containing L-arginine 57 2002
* 7,087,263 Rare limiting barriers for implantable medical devices 19 2002
* 2004/0072,922 Rate limiting barriers for implantable medical devices 155 2002
7,776,926 Biocompatible coating for implantable medical devices 39 2002
7,094,256 Coatings for implantable medical device containing polycationic peptides 46 2002
7,258,891 Stent mounting assembly and a method of using the same to coat a stent 24 2003
7,279,174 Stent coatings comprising hydrophilic additives 92 2003
* 2004/0224,001 Stent coatings comprising hydrophilic additives 132 2003
* 2005/0021,127 Porous glass fused onto stent for drug retention 64 2003
* 7,431,959 Method and system for irradiation of a drug eluting implantable medical device 20 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 70 2003
9,114,198 Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same 0 2003
* 2005/0106,204 Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same 41 2003
8,192,752 Coatings for implantable devices including biologically erodable polyesters and methods for fabricating the same 4 2003
* 2005/0112,171 Coatings for implantable devices including biologically erodable polyesters and methods for fabricating the same 64 2003
7,220,816 Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same 53 2003
* 2005/0131,201 Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same 15 2003
7,435,788 Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents 12 2003
* 2005/0137,381 Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents 29 2003
7,563,324 System and method for coating an implantable medical device 53 2003
7,820,190 Coating for implantable devices and a method of forming the same 9 2004
8,685,431 Biologically absorbable coatings for implantable devices based on copolymers having ester bonds and methods for fabricating the same 1 2004
* 2005/0208,091 Biologically absorbable coatings for implantable devices based on copolymers having ester bonds and methods for fabricating the same 41 2004
8,349,388 Method of coating a stent 1 2004
7,758,880 Biocompatible polyacrylate compositions for medical applications 1 2004
7,364,748 Controlled morphologies in polymer drug for release of drugs from polymer films 4 2004
7,485,334 Stent mandrel fixture and method for minimizing coating defects 5 2004
6,972,054 Coupling device for a stent support fixture 34 2004
* 2004/0191,405 Stent mandrel fixture and method for minimizing coating defects 36 2004
7,807,210 Hemocompatible polymers on hydrophobic porous polymers 5 2004
7,553,377 Apparatus and method for electrostatic coating of an abluminal stent surface 20 2004
8,293,890 Hyaluronic acid based copolymers 1 2004
7,820,732 Methods for modulating thermal and mechanical properties of coatings on implantable devices 8 2004
* 2005/0245,637 Methods for modulating thermal and mechanical properties of coatings on implantable devices 90 2004
* 2005/0244,363 Hyaluronic acid based copolymers 28 2004
7,785,512 Method and system of controlled temperature mixing and molding of polymers with active agents for implantable medical devices 12 2004
* 2005/0265,960 Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same 52 2004
7,807,211 Thermal treatment of an implantable medical device 12 2004
* 2005/0266,038 Antifouling heparin coatings 33 2004
* 2005/0233,062 Thermal treatment of an implantable medical device 72 2004
* 2005/0271,700 Poly(ester amide) coating composition for implantable devices 44 2004
7,563,780 Heparin prodrugs and drug delivery stents formed therefrom 4 2004
7,077,860 Method of reducing or eliminating thrombus formation 34 2004
* 2006/0002,968 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders 20 2004
7,297,159 Selective coating of medical devices 11 2004
8,357,391 Coatings for implantable devices comprising poly (hydroxy-alkanoates) and diacid linkages 5 2004
7,494,665 Polymers containing siloxane monomers 6 2004
* 2006/0034,888 Coatings for implantable devices comprising poly (hydroxy-alkanoates) and diacid linkages 28 2004
7,311,980 Polyactive/polylactic acid coatings for an implantable device 24 2004
7,648,727 Methods for manufacturing a coated stent-balloon assembly 7 2004
* 2006/0043,650 Methods for manufacturing a coated stent-balloon assembly 13 2004
7,244,443 Polymers of fluorinated monomers and hydrophilic monomers 18 2004
8,110,211 Medicated coatings for implantable medical devices including polyacrylates 2 2004
* 2006/0062,824 Medicated coatings for implantable medical devices including polyacrylates 12 2004
8,052,912 Temperature controlled crimping 1 2004
7,166,680 Blends of poly(ester amide) polymers 31 2004
* 2006/0074,191 Blends of poly(ester amide) polymers 11 2004
7,481,835 Encapsulated covered stent 9 2004
7,390,497 Poly(ester amide) filler blends for modulation of coating properties 16 2004
* 2006/0093,842 Poly(ester amide) filler blends for modulation of coating properties 16 2004
* 2006/0095,122 Implantable devices comprising biologically absorbable star polymers and methods for fabricating the same 14 2004
7,214,759 Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same 14 2004
* 2006/0111,546 Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same 3 2004
8,609,123 Derivatized poly(ester amide) as a biobeneficial coating 0 2004
* 2006/0115,513 Derivatized poly(ester amide) as a biobeneficial coating 19 2004
7,892,592 Coating abluminal surfaces of stents and other implantable medical devices 2 2004
* 2006/0115,449 Bioabsorbable, biobeneficial, tyrosine-based polymers for use in drug eluting stent coatings 51 2004
7,632,307 Abluminal, multilayer coating constructs for drug-delivery stents 13 2004
7,604,818 Polymers of fluorinated monomers and hydrocarbon monomers 3 2004
* 2006/0134,165 Polymers of fluorinated monomers and hydrocarbon monomers 53 2004
8,741,378 Methods of coating an implantable device 0 2004
7,419,504 Poly(ester amide) block copolymers 16 2004
* 2006/0142,541 Poly(ester amide) block copolymers 15 2004
8,007,775 Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same 6 2004
* 2006/0147,412 Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same 22 2004
7,202,325 Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles 38 2005
* 2006/0160,985 POLY(HYDROXYALKANOATE-CO-ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES 14 2005
7,387,810 Method of forming rate limiting barriers for implantable devices 13 2005
7,063,884 Stent coating 33 2005
* 2005/0186,248 Stent coating 1 2005
7,758,881 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 6 2005
* 2005/0238,686 Coating for implantable devices and a method of forming the same 26 2005
7,795,467 Bioabsorbable, biobeneficial polyurethanes for use in medical devices 11 2005
8,778,375 Amorphous poly(D,L-lactide) coating 0 2005
7,637,941 Endothelial cell binding coatings for rapid encapsulation of bioerodable stents 24 2005
7,691,401 Poly(butylmethacrylate) and rapamycin coated stent 31 2005
7,622,070 Method of manufacturing an implantable polymeric medical device 55 2005
7,823,533 Stent fixture and method for reducing coating defects 4 2005
8,021,676 Functionalized chemically inert polymers for coatings 3 2005
8,067,023 Implantable medical devices incorporating plasma polymerized film layers and charged amino acids 0 2005
7,785,647 Methods of providing antioxidants to a drug containing product 1 2005
* 2007/0020,380 Methods of providing antioxidants to a drug containing product 28 2005
7,735,449 Stent fixture having rounded support structures and method for use thereof 13 2005
7,875,286 Polycationic peptide coatings and methods of coating implantable medical devices 0 2005
7,803,406 Polycationic peptide coatings and methods of coating implantable medical devices 0 2005
* 2006/0002,974 Polycationic peptide coatings and methods of coating implantable medical devices 4 2005
7,794,743 Polycationic peptide coatings and methods of making the same 4 2005
* 2006/0062,821 Polycationic peptide coatings and methods of making the same 23 2005
7,985,440 Method of using a mandrel to coat a stent 6 2005
7,396,541 Heparin prodrugs and drug delivery stents formed therefrom 3 2005
* 2006/0014,720 Heparin prodrugs and drug delivery stents formed therefrom 8 2005
* 2007/0128,246 Solventless method for forming a coating 14 2005
* 2007/0135,909 Adhesion polymers to improve stent retention 3 2005
7,976,891 Abluminal stent coating apparatus and method of using focused acoustic energy 4 2005
7,591,841 Implantable devices for accelerated healing 3 2005
7,867,547 Selectively coating luminal surfaces of stents 0 2005
7,638,156 Apparatus and method for selectively coating a medical article 30 2005
7,601,383 Coating construct containing poly (vinyl alcohol) 3 2006
* 2007/0202,323 Coating construct containing poly (vinyl alcohol) 18 2006
7,713,637 Coating containing PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid polymer 2 2006
* 2007/0207,181 Coating containing PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid polymer 3 2006
* 2007/0231,363 Coatings formed from stimulus-sensitive material 6 2006
8,304,012 Method for drying a stent 2 2006
8,069,814 Stent support devices 6 2006
8,003,156 Rotatable support elements for stents 14 2006
* 2007/0259,102 Methods and devices for coating stents 6 2006
7,648,725 Clamp mandrel fixture and a method of using the same to minimize coating defects 8 2006
7,572,336 Clamp mandrel fixture and a method of using the same to minimize coating defects 4 2006
7,775,178 Stent coating apparatus and method 1 2006
* 2008/0226,812 Stent coating apparatus and method 5 2006
8,568,764 Methods of forming coating layers for medical devices utilizing flash vaporization 1 2006
* 2007/0280,988 Coating layers for medical devices and methods of making the same 13 2006
8,703,167 Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug 0 2006
8,778,376 Copolymer comprising elastin pentapeptide block and hydrophilic block, and medical device and method of treating 0 2006
* 2007/0286,882 Solvent systems for coating medical devices 14 2006
8,114,150 RGD peptide attached to bioabsorbable stents 1 2006
9,028,859 Phase-separated block copolymer coatings for implantable medical devices 0 2006
7,357,793 Polymers of fluorinated and hydrophilic monomers 37 2006
* 2007/0016,284 Polymeric coating for reducing the rate of release of a therapeutic substance from a stent 5 2006
8,961,588 Method of coating a stent with a release polymer for 40-O-(2-hydroxy)ethyl-rapamycin 0 2006
* 8,173,199 40-O-(2-hydroxy)ethyl-rapamycin coated stent 2 2006
* 2007/0026,131 40-O-(2-hydroxy)ethyl-rapamycin coated stent 3 2006
* 2007/0020,382 40-O-(2-hydroxy)ethyl-rapamycin coated stent 16 2006
7,803,394 Polycationic peptide hydrogel coatings for cardiovascular therapy 1 2006
7,365,133 Blends of poly(ester amide) polymers 0 2006
* 2007/0093,617 Blends of poly(ester amide) polymers 5 2006
8,597,673 Coating of fast absorption or dissolution 1 2006
* 2008/0145,393 Coating of fast absorption or dissolution 8 2006
8,197,879 Method for selectively coating surfaces of a stent 1 2007
7,604,700 Stent mandrel fixture and method for selectively coating surfaces of a stent 2 2007
7,361,726 Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles 11 2007
8,067,025 Nitric oxide generating medical devices 2 2007
* 2007/0167,602 Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same 5 2007
7,538,180 Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same 2 2007
* 2007/0249,801 Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same 2 2007
7,901,703 Polycationic peptides for cardiovascular therapy 0 2007
8,017,140 Drug-delivery stent formulations for restenosis and vulnerable plaque 0 2007
7,766,884 Polymers of fluorinated monomers and hydrophilic monomers 1 2007
9,175,162 Methods for forming stent coatings comprising hydrophilic additives 0 2007
* 2008/0118,543 Stent Coatings comprising hydrophilic additives 18 2007
* 2008/0021,008 Stent coatings comprising hydrophilic additives 34 2007
* 2008/0167,712 POLY(ESTER AMIDE) FILLER BLENDS FOR MODULATION OF COATING PROPERTIES 1 2008
7,520,891 Blends of poly(ester amide) polymers 1 2008
7,507,251 Blends of poly(ester amide) polymers 0 2008
7,699,889 Poly(ester amide) block copolymers 0 2008
7,887,871 Method and system for irradiation of a drug eluting implantable medical device 0 2008
* 2008/0317,939 Method and System for Irradiation of a Drug Eluting Implantable Medical Device 7 2008
7,786,249 Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents 0 2008
7,772,359 Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents 0 2008
7,632,914 Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents 0 2008
8,580,180 Polymeric stent polishing method and apparatus 1 2009
* 2010/0198,342 COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME 1 2010
* 2011/0001,271 Thermal Treatment Of An Implantable Medical Device 11 2010
* 2011/0003,068 Thermal Treatment Of An Implantable Medical Device 3 2010
8,586,125 Thermal treatment of an implantable medical device 2 2010
* 2011/0008,529 Thermal Treatment Of An Implantable Medical Device 5 2010
8,293,367 Nanoshells on polymers 1 2011
8,741,379 Rotatable support elements for stents 1 2011
8,637,110 Rotatable support elements for stents 1 2011
8,596,215 Rotatable support elements for stents 1 2011
8,465,789 Rotatable support elements for stents 1 2011
* 2012/0291,703 STENT COATING APPARATUS 0 2012
9,084,671 Methods of forming a micronized peptide coated stent 0 2013
 
SURMODICS, INC. (4)
7,550,443 Process and systems for biocompatible surfaces 3 2005
7,550,444 Composition and method for preparing biocompatible surfaces 3 2005
* 2005/0244,453 Composition and method for preparing biocompatible surfaces 40 2005
* 2005/0232,970 Process and systems for biocompatible surfaces 8 2005
 
ROCHE DIAGNOSTICS OPERATIONS, INC. (1)
9,101,689 Primer coatings for stents with oxide, anionic, or hydroxyl surface moieties 0 2010
 
Biotronik Mess- und Therapiegeraete GmbH & Co. Ingenieurbuero (1)
* 2004/0034,409 Stent with polymeric coating 57 2003
 
DEPUY SYNTHES PRODUCTS, INC. (1)
8,900,620 Drug-impregnated encasement 0 2006
 
ADVANCED COARDIOVASCULAR SYSTEMS, INC. (1)
* 2005/0287,184 Drug-delivery stent formulations for restenosis and vulnerable plaque 30 2004
 
ZORION MEDICAL, INC. (2)
8,888,841 Bioabsorbable implants 0 2011
8,986,369 Magnesium-based absorbable implants 0 2011
 
WYETH (8)
7,261,735 Local drug delivery devices and methods for maintaining the drug coatings thereon 62 2001
* 2002/0165,608 Local drug delivery devices and methods for maintaining the drug coatings thereon 87 2001
8,303,609 Coated medical devices 0 2001
* 7,195,640 Coated medical devices for the treatment of vulnerable plaque 78 2002
* 2003/0060,877 Coated medical devices for the treatment of vascular disease 88 2002
8,182,527 Heparin barrier coating for controlled drug release 1 2004
* 2006/0222,756 Medical devices, drug coatings and methods of maintaining the drug coatings thereon 17 2006
* 2006/0235,503 Local drug delivery devices and methods for maintaining the drug coatings thereon 2 2006
 
Cardiac Pacemakers, Inc. (1)
8,696,564 Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth 0 2004
 
Ciba Specialty Chemicals Corporation (1)
* 2002/0198,344 Stabilized medium and high voltage cable insulation composition 0 2002
 
MEDTRONIC AVE, INC. (1)
* 2003/0204,239 Endovascular stent with a preservative coating 49 2002
 
CONOR MEDSYSTEMS, INC. (4)
7,208,010 Expandable medical device for delivery of beneficial agent 36 2001
* 2002/0082,680 Expandable medical device for delivery of beneficial agent 25 2001
7,208,011 Implantable medical device with drug filled holes 80 2002
* 2003/0068,355 Therapeutic agent delivery device with protective separating layer 20 2002
 
Sahajanand Medical Technologies Pvt. Ltd. (1)
* 2007/0212,387 COATINGS FOR IMPLANTABLE MEDICAL DEVICES 17 2007
 
ABBOTT LABORATORIES (8)
9,296,011 Prosthesis having varied concentration of beneficial agent 0 2003
7,597,764 System of loading beneficial agent to a prosthesis by fluid-jet 5 2006
8,524,148 Method of integrating therapeutic agent into a bioerodible medical device 1 2006
* 8,221,495 Integration of therapeutic agent into a bioerodible medical device 7 2006
* 2007/0191,943 Integration Of Therapeutic Agent Into A Bioerodible Medical Device 57 2006
7,645,476 Method of loading beneficial agent to a prosthesis by fluid-jet application 2 2007
* 2009/0093,875 DRUG ELUTING STENTS WITH PROLONGED LOCAL ELUTION PROFILES WITH HIGH LOCAL CONCENTRATIONS AND LOW SYSTEMIC CONCENTRATIONS 6 2008
8,001,926 System and method of loading and detecting beneficial agent on a prosthesis 2 2009
 
BOSTON SCIENTIFIC SCIMED, INC. (11)
8,118,861 Bifurcation stent and balloon assemblies 1 2007
7,842,082 Bifurcated stent 2 2007
7,951,191 Bifurcated stent with entire circumferential petal 0 2007
7,959,669 Bifurcated stent with open ended side branch support 1 2007
7,833,266 Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment 0 2007
8,277,501 Bi-stable bifurcated stent petal geometry 5 2007
7,815,675 Stent with protruding branch portion for bifurcated vessels 3 2008
8,932,340 Bifurcated stent and delivery system 0 2008
8,016,878 Bifurcation stent pattern 0 2009
7,951,192 Stent with protruding branch portion for bifurcated vessels 5 2009
8,425,590 Stent with protruding branch portion for bifurcated vessels 0 2011
 
INNOVATIONS HOLDINGS, L.L.C. (27)
7,819,912 Expandable medical device with beneficial agent delivery mechanism 0 2003
* 2003/0167,085 Expandable medical device with beneficial agent delivery mechanism 24 2003
7,056,338 Therapeutic agent delivery device with controlled therapeutic agent release rates 88 2003
* 2004/0193,255 Therapeutic agent delivery device with controlled therapeutic agent release rates 7 2003
* 2004/0143,322 Method and apparatus for treating vulnerable artherosclerotic plaque 61 2003
* 2004/0142,014 Method and apparatus for reducing tissue damage after ischemic injury 73 2003
* 2004/0122,506 Expandable medical device for delivery of beneficial agent 49 2003
* 2005/0010,170 IMPLANTABLE MEDICAL DEVICE WITH BENEFICIAL AGENT CONCENTRATION GRADIENT 5 2004
* 2004/0204,756 ABSORBENT ARTICLE WITH IMPROVED LIQUID ACQUISITION CAPACITY 14 2004
* 2004/0202,692 Implantable medical device and method for in situ selective modulation of agent delivery 79 2004
7,896,912 Expandable medical device with S-shaped bridging elements 2 2004
D516723 Stent wall structure 17 2004
7,517,362 Therapeutic agent delivery device with controlled therapeutic agent release rates 4 2004
* 2005/0058,684 Therapeutic agent delivery device with controlled therapeutic agent release rates 20 2004
D523558 Stent wall structure 17 2005
8,187,321 Expandable medical device for delivery of beneficial agent 0 2005
* 2006/0008,503 Therapeutic agent delivery device with controlled therapeutic agent release rates 12 2005
7,850,727 Expandable medical device for delivery of beneficial agent 5 2005
7,850,728 Expandable medical device for delivery of beneficial agent 2 2006
8,449,901 Implantable medical device with beneficial agent concentration gradient 0 2006
* 2006/0178,735 Expandable medical device and method for treating chronic total occlusions with local delivery of an angiogenic factor 12 2006
* 2007/0219,628 Implantable Medical Device with Drug Filled Holes 12 2007
8,361,537 Expandable medical device with beneficial agent concentration gradient 3 2007
* 2008/0097,581 EXPANDABLE MEDICAL DEVICE WITH BENEFICIAL AGENT CONCENTRATION GRADIENT 25 2007
8,206,435 Expandable medical device for delivery of beneficial agent 2 2009
8,439,968 Expandable medical device for delivery of beneficial agent 2 2011
8,623,068 Expandable medical device with ductile hinges 0 2011
 
T-RAM SEMICONDUCTOR, INC. (1)
* 2003/0129,215 Medical devices containing rapamycin analogs 38 2002
 
Medtronic Vascular, Inc. (1)
* 2005/0154,451 Medical devices to treat or inhibit restenosis 3 2004
 
CONOR MEDSYSTEMS, LLC (1)
7,909,865 Expandable medical device for delivery of beneficial agent 3 2009
 
CHEVRON U.S.A. INC. (1)
* 2010/0167,916 IONIC LIQUID CATALYST COMPRISING AN ALKYL-PYRIDINIUM HALOALUMINATE AND AN IMPURITY 0 2009
* Cited By Examiner