Methods for screening compound libraries
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United States of America Patent
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Apr 13, 2004
Grant Date -
N/A
app pub date -
Mar 25, 1999
filing date -
Mar 27, 1998
priority date (Note) -
Expired
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Abstract
Disclosed are methods for screening compound libraries using frontal chromatography in combination with mass spectrometry to identify and rank those members of the library that bind to a target receptor. Methods are also disclosed which permit a compound library to be rapidly screened to determine if any member of the library has an affinity for the target receptor as measured by a pre-selected indicator compound.
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