Process for preparing optically active amino acid derivatives

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United States of America Patent

PATENT NO 6720449
APP PUB NO 20030032814A1
SERIAL NO

09926346

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Abstract

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An optically active amino acid derivative is produced by N-protecting an optically active 3-haloalanine derivative followed by cyclization, or cyclizing this derivative followed by N-protection to thereby give an optically active N-protected-aziridine-2-carboxylic acid derivative which is protected by a benzenesulfonyl group substituted by nitro at the 2-and/or 4-positions and then treating this product with an organic metal reagent, or by N-protecting an optically active 3-haloalanine derivative to thereby give N-protected-aziridine-2-carboxylic acid which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent. According to this process, natural and unnatural optically active amino acids can be produced from inexpensive materials by using simple procedures.

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Patent Owner(s)

Patent OwnerAddress
KANEKA CORPORATION2-3-18 NAKANOSHIMA KITA-KU OSAKA-SHI OSAKA 530-8288

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujii, Akio Hyogo, JP 119 1152
Fuse, Yoshihide Hyogo, JP 22 64
Inoue, Kenji Hyogo, JP 229 2017
Kinoshita, Koichi Hyogo, JP 97 1351
Moroshima, Tadashi Hyogo, JP 22 33
Nagashima, Nobuo Hyogo, JP 23 31
Okuro, Kazumi Hyogo, JP 12 11
Saka, Yasuhiro Hyogo, JP 6 13
Sugawara, Masanobu Chiba, JP 9 7
Takeda, Toshihiro Hyogo, JP 25 74
Ueda, Yasuyoshi Hyogo, JP 103 603

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