Oligosaccharide synthesis
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United States of America Patent
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Apr 20, 2004
Grant Date -
Feb 6, 2003
app pub date -
Aug 30, 2002
filing date -
Aug 26, 1996
priority date (Note) -
Expired
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Abstract
The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to couple saccharide groups of both the O-glycoside and N-glycoside type to a polymer support. The invention provides reagents, reagent kits and methods for solid-phase oligosaccharide synthesis.
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