Methods and devices for sealing microchip reservoir devices

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6730072
APP PUB NO 20020151776A1
SERIAL NO

09867976

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Abstract

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Methods and devices are provided for mechanically sealing the reservoirs of microchip devices to prevent leakage from or between any of the reservoirs. In one embodiment, the method includes sandwiching a microchip device and a gasket material covering the reservoir openings between a front sealing frame and a backplate, such that the gasket material is compressed against the back side of the microchip device by the back plate. The front sealing frame is secured to the back sealing plate using fasteners or welding. The gasket material is preferably a flexible polymeric sheet, which is biocompatible and compatible with the reservoir contents. In another embodiment, a composite backplate is used in place of the back sealing plate and separate gasket material. The composite backplate can include a substrate having sealing plugs defined thereon. The composite backplate also can be designed to hold the drug, thereby combining the assembly steps of reservoir filling and sealing.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cima, Michael J Winchester, MA 151 10097
Herman, Stephen J Andover, MA 52 6544
Polito, Benjamin F Cambridge, MA 18 1300
Santini, Jr John T Belmont, MA 24 4035
Shawgo, Rebecca S Cambridge, MA 1 104
Sheppard, Jr Norman F Bedford, MA 20 2171
Uhland, Scott A Somerville, MA 40 2741

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