Conjugate of polyethylene glycol and chitosan
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United States of America Patent
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May 4, 2004
Grant Date -
Sep 4, 2003
app pub date -
Jan 24, 2003
filing date -
Jul 3, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
PEG-chitosan conjugates comprising chitosan and polyethylene glycol moieties or derivatives thereof which are bonded together and their use in medicine is described. In one embodiment, the conjugate comprises a chitosan moiety or a derivative thereof and a polyethylene glycol moiety or a derivative thereof which are bonded together via the amino function on the chitosan by the use of an activated chitosan species. In another embodiment, the conjugate comprises a chitosan moiety or a derivative thereof and a polyethylene glycol moiety or a derivative thereof which are bonded together, the chitosan portion of the conjugate having a molecular weight in the range of from 10 kilodaltons to 1000 kilodaltons.
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