US Patent No: 6,737,042
Number of patents in Portfolio can not be more than 2000
Delivery of drug esters through an inhalation route
Stats
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May 18, 2004
Issued date -
May 13, 2002
filing date -
10/146,516
serial no -
Expired
status
Importance
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Abstract
The present invention relates to the delivery of drug esters through an inhalation route. Specifically, it relates to aerosols containing drug esters that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of drug ester. In a method aspect of the present invention, a drug ester is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of drug ester, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering a drug ester through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of drug ester; and, b) a device that forms a drug ester containing aerosol from the composition, for inhalation by the mammal.
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First Claim
Related Publications
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 5,544,646 Systems for the intrapulmonary delivery of aerosolized aqueous formulations | 191 | 1994 | |
| 5,957,124 Dynamic particle size control for aerosolized drug delivery | 162 | 1995 | |
| 5,694,919 Lockout device for controlled release of drug from patient-activated dispenser | 153 | 1995 | |
| 5,915,378 Creating an aerosolized formulation of insulin | 135 | 1995 | |
| 5,934,272 Device and method of creating aerosolized mist of respiratory drug | 173 | 1995 | |
| 5,960,792 Device for aerosolized delivery of peptide drugs | 165 | 1995 | |
| 5,735,263 Lockout device for controlled release of drug from patient-activated dispenser | 167 | 1996 | |
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| 5,099,861 Aerosol delivery article | 117 | 1990 | |
| 5,388,574 Aerosol delivery article | 136 | 1993 | |
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| 5,655,523 Dry powder inhalation device having deagglomeration/aerosolization structure responsive to patient inhalation | 143 | 1995 | |
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| 4,654,370 Glyceryl valproates | 25 | 1980 | |
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| 6,095,153 Vaporization of volatile materials | 150 | 1998 | |
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| 5,607,691 Compositions and methods for enhanced drug delivery | 136 | 1995 | |
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| 2003/0032,638 Delivery of benzodiazepines through an inhalation route | 110 | 2002 | |
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| 5,622,944 Testosterone prodrugs for improved drug delivery | 52 | 1995 | |
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| 5,126,123 Aerosol drug formulations | 112 | 1991 | |
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| 5,758,637 Liquid dispensing apparatus and methods | 170 | 1996 | |
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| 6,506,765 Apomorphine derivatives and methods for their use | 2 | 2001 | |
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| 5,767,117 Method for treating vascular headaches | 71 | 1994 | |
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| 5,166,202 Method for the treatment of panic disorder | 48 | 1991 | |
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| 4,588,721 Treatment of negative symptoms of schizophrenia | 40 | 1984 | |
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| RE30285 Spraying devices, in particular nebulizing devices | 112 | 1977 | |
| 5,017,575 Treatment of immunologically based disorders, specifically Crohn's disease | 34 | 1987 | |
| 4,863,720 Pharmaceutical preparation and methods for its production | 58 | 1987 | |
| 4,848,374 Smoking device | 126 | 1988 | |
| 5,543,434 Nasal administration of ketamine to manage pain | 57 | 1994 | |
| 6,048,857 Dosing method of administering medicaments via inhalation administration | 45 | 1998 | |
| 6,140,323 Dosing method of administering medicaments via inhalation administration or skin administration | 41 | 1999 | |
| 6,591,839 Filter material for reducing harmful substances in tobacco smoke | 107 | 2001 | |
| 2003/0004,142 Use of NSAIDs for prevention and treatment of cellular abnormalities of the lung or bronchial pathway | 96 | 2002 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Nov 18, 2015 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |