Thiol sulfonamide metalloprotease inhibitors

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United States of America Patent

PATENT NO 6747027
SERIAL NO

08898175

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Abstract

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This invention is directed to proteinase (protease) inhibitors, and more particularly to thiol sulfonamide inhibitors for matrix metalloproteinase 13(MMP-13), compositions of proteinase inhibitors, intermediates for the syntheses of proteinase inhibitors, processes for the preparation of proteinase inhibitors and processes for treating pathological conditions associated with pathological matrix metalloproteinase activity related to MMP-13.

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Patent Owner(s)

Patent OwnerAddress
MONSANTO COMPANY800 N LINDBERGH BOULEVARD ST LOUIS MO 63167

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abbas, Zaheer S Chesterfield, MO 2 2
DeCrescenzo, Gary St. Charles, MO 14 3
Freskos, John N Clayton, MO 144 1210
Getman, Daniel P Chesterfield, MO 158 1018
Heintz, Robert M Ballwin, MO 63 496
McDonald, Joseph J Ballwin, MO 67 329
Mischke, Brent V Defiance, MO 14 73

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