Thiol sulfonamide metalloprotease inhibitors

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United States of America Patent

PATENT NO 6747027
SERIAL NO

08898175

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention is directed to proteinase (protease) inhibitors, and more particularly to thiol sulfonamide inhibitors for matrix metalloproteinase 13(MMP-13), compositions of proteinase inhibitors, intermediates for the syntheses of proteinase inhibitors, processes for the preparation of proteinase inhibitors and processes for treating pathological conditions associated with pathological matrix metalloproteinase activity related to MMP-13.

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Patent Owner(s)

  • MONSANTO COMPANY;PHARMACIA CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abbas, Zaheer S Chesterfield, MO 2 2
DeCrescenzo, Gary St. Charles, MO 25 28
Freskos, John N Clayton, MO 145 1273
Getman, Daniel P Chesterfield, MO 158 1062
Heintz, Robert M Ballwin, MO 63 512
McDonald, Joseph J Ballwin, MO 67 382
Mischke, Brent V Defiance, MO 14 82

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