Increased drug-loading and reduced stress drug delivery device
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United States of America Patent
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Jul 6, 2004
Grant Date -
N/A
app pub date -
Oct 30, 2000
filing date -
Oct 30, 2000
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
An implantable prosthesis, for example a stent, is provided having one or more elements that form the body structure of the prosthesis. The elements have a width that is variable from a nominal or conventional width to an increased width. Depots are formed in the elements and are generally located at the increased width portions of the elements. The diameter of the depots is based on a percentage of the width of the element. As such, the depots have increased drug-loading capabilities. Substances such as therapeutic substances, polymeric materials, polymeric materials containing therapeutic substances, radioactive isotopes, and radiopaque materials can be deposited into the depots. Further, the variable width of the elements ensures that sufficient material surrounds each depot so as not to compromise the structural integrity of the prosthesis.
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