Detection of human hepatitis B virus surface antigen mutants by specific amplification and its application on gene chip
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United States of America Patent
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Jul 6, 2004
Grant Date -
Jan 2, 2003
app pub date -
Jul 28, 1999
filing date -
Jul 28, 1999
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Abstract
Novel DNA probe sequences for detection, by polymerase chain reaction, of human hepatitis B virus surface antigen mutant 145 (Glycine to Arginine) from serum samples. As a direct application, these specific DNA probes are immobilized on solid glass supports (gene chip) for detection of human hepatitis B virus surface antigen mutant 145 (Glycine to Arginine) by fluorescence.
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