Polynucleotides encoding the fkbA gene of the FK-520 polyketide synthase gene cluster

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United States of America Patent

PATENT NO 6759536
APP PUB NO 20030175901A1
SERIAL NO

09940316

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Abstract

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Host cells comprising recombinant vectors encoding the FK-520 polyketide synthase and FK-520 modification enzymes can be used to produce the FK-520 polyketide. Recombinant DNA constructs comprising one or more FK-520 polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variety of different polyketides with application as pharmaceutical and veterinary products.

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Patent Owner(s)

Patent OwnerAddress
KOSAN BIOSCIENCES INC3832 BAY CENTER PLACE INTELLECTUAL PROPERTY DEPT HAYWARD CA 94545

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chu, Daniel Santa Clara, CA 95 645
Khosla, Chaitan Palo Alto, CA 123 1815
Reeves, Christopher Orinda, CA 22 79
Santi, Daniel San Francisco, CA 30 273
Wu, Kai Foster City, CA 492 3966

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