Adjuvant compositions containing more than one adjuvant
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United States of America Patent
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Jul 20, 2004
Grant Date -
N/A
app pub date -
Jun 16, 1994
filing date -
Jun 16, 1994
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Adjuvant compositions for modulating an immune response to an antigen administered to a host comprise a mineral salt adjuvant and at least one other adjuvant. The compositions provide an adjuvanting effect on an antigen which is greater than the adjuvanting effect attainable by one of the adjuvants alone. An antigen is covalently bonded to a glycolipid analog to provide a discrete molecule which exhibits an enhanced adjuvanting effect on the antigen which is greater than the adjuvanting effect attainable in the absence of such covalent bonding.
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