Microchip reservoir devices and facilitated corrosion of electrodes
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Aug 10, 2004
Grant Date -
Sep 26, 2002
app pub date -
Oct 11, 2001
filing date -
Oct 11, 2000
priority date (Note) -
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Abstract
Methods and devices are provided for enhancing corrosion of an electrode in a biocompatible fluid. The method comprises (1) placing a primary electrode and a counter electrode in an electroconductive biocompatible fluid to form an electrochemical cell; and (2) applying a time-varying potential, through the electrochemical cell, to the primary electrode. In a preferred embodiment, the primary electrode is metal and comprises a reservoir cap of a microchip device for the release of molecules or exposure of device reservoir contents. The potential preferably is characterized by a waveform having a maximum potential effectively anodic to meet or exceed the corrosion potential of the primary electrode. Also, the minimum potential preferably is effectively cathodic to be below the value where re-deposition of metal ions on the metal electrode can substantially occur, thereby corroding the metal electrode.
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