Liposomal compositions, and methods of using liposomal compositions to treat dislipidemias
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United States of America Patent
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Aug 10, 2004
Grant Date -
Aug 15, 2002
app pub date -
Aug 7, 2001
filing date -
Mar 4, 1994
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides a liposomal composition for treating dislipidemias in human subjects, a method of using a liposomal composition, and devices and modes of operation of the devices and of the compositions, and kits related thereto. The invention provides for the reverse transport of cholesterol from peripheral tissues to the liver in a warm blood mammal while controlling plasma atherogenic lipoprotein concentrations, including LDL concentrations. A method described above and mode of operation of the devices includes the stop of administering an effective amount of a multiplicity of acceptors comprised of phospholipids substantially free of sterol. A method described above optionally includes the stop of periodically assaying atherogenic lipoprotein concentrations with an assay during the treatment period to assess atherogenic lipoprotein concentrations and obtain an atherogenic lipoprotein profile.
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