Kinesin motor modulators derived from the marine sponge Adocia

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United States of America Patent

PATENT NO 6777200
APP PUB NO 20030127621A1
SERIAL NO

10305857

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.

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Patent Owner(s)

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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA1111 FRANKLIN STREET 5TH FLOOR OAKLAND CA 94607-5200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berdelis, Michael S Downey, CA 4 58
Blackburn, Christine L San Diego, CA 4 58
Faulkner, David John La Jolla, CA 4 58
Goldstein, Lawrence S B San Diego, CA 10 58
Hopmann, Cordula Frankfurt am Main, DE 11 62
Sakowicz, Roman Foster City, CA 58 275

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