Iterative optimization in the design of binding proteins

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United States of America Patent

PATENT NO 6794136
SERIAL NO

09716637

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Abstract

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Disclosed herein are design methods for optimizing the specificity of a binding protein. The methods comprise iterative cycles of rational design, site selection, redesign and site selection of the redesigned molecule.

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Patent Owner(s)

Patent OwnerAddress
SANGAMO BIOSCIENCES INC7000 MARINA BLVD BRISBANE CA 94005

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eisenberg, Stephen P Boulder, CO 36 3223
Jamieson, Andrew San Francisco, CA 28 1474
Liu, Qiang Foster City, CA 382 3076
Rebar, Edward El Cerrito, CA 20 707

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