Methods for systematic identification of protein--protein interactions
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United States of America Patent
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Sep 28, 2004
Grant Date -
Aug 1, 2002
app pub date -
Nov 30, 2000
filing date -
Nov 30, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to a method for identifying protein--protein interactions. The interacting proteins are isolated by affinity chromatography and identified by mass spectrometry. The affinity chromatography method allows for the purification of unknown interacting proteins which are identified using mass spectrometric techniques. The invention provides a method for the high throughput analysis of protein--protein interactions that lends itself to automation.
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