Method of monitoring a biological system by labeling with an apo metal binding protein

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United States of America Patent

PATENT NO 6800437
SERIAL NO

09633232

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is directed to reporter molecules and tags that may be used to monitor a target substance in a biological system. More particularly, the present invention relates to the use of an apo metal binding protein as a reporter molecule or tag. An apo metal binding protein may be bound to a protein or tissue or introduced into a cell. The invention also relates to methods of utilizing the apo metal binding protein for detecting a cell expressing a protein of interest, localizing a protein in a cell, and designing a therapeutic agent for treating a disease or infection.

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Patent Owner(s)

Patent OwnerAddress
TIBOTEC N VMECHELEN MECHELEN ANTWERP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Kerpel Jan Octaaf Antoon Lede, BE 4 15
Dierynck, Inge Wilrijk, BE 14 141
Pauwels, Rudi Wilfried Jan Bonheiden, BE 11 52
Roelant, Christiaan Hubert Simon Leuven, BE 11 81
Van, Acker Koenraad Lodewijk August Temso, BE 11 19

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