Wound healing compositions and methods using tropoelastin and lysyl oxidase
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United States of America Patent
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Oct 26, 2004
Grant Date -
Oct 17, 2002
app pub date -
Feb 4, 2000
filing date -
Feb 4, 2000
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Abstract
The present invention provides compositions and methods for promoting wound healing. The composition comprises virgin monomers of tropoelastin and lysyl oxidase. When the lysyl oxidase comes in contact with the tropoelastin, cross-linking of the tropoelastin monomers will occur to form elastin. Contacting the tropoelastin and lysyl oxidase together and applying the mixture to a wound before substantial cross-linking has occurred promotes wound healing by holding the damaged tissue together, increasing the rate of healing, and decreasing the amount of scarring.
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