US Patent No: 6,814,954

Number of patents in Portfolio can not be more than 2000

Delivery of compounds for the treatment of Parkinsons through an inhalation route

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to the delivery of compounds for the treatment of Parkinsons through an inhalation route. Specifically, it relates to aerosols containing antiparkinsonian drugs that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of an antiparkinsonian drug. In a method aspect of the present invention, an antiparkinsonian drug is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of an antiparkinsonian drug to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering an antiparkinsonian drug through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of an antiparkinsonian drug; and, b) a device that forms an antiparkinsonian drug containing aerosol from the composition, for inhalation by the mammal.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
ALEXZA PHARMACEUTICALS, INC.PALO ALTO, CA62

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rabinowitz, Joshua D Mountain View, CA 142 7750
Zaffaroni, Alejandro C Atherton, CA 107 6677

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (2)
6,313,176 Dosing method of administering deprenyl via intraoral administration or inhalation administration 32 2000
6,591,839 Filter material for reducing harmful substances in tobacco smoke 114 2001
 
ALEXZA PHARMACEUTICALS, INC. (1)
2003/0032,638 Delivery of benzodiazepines through an inhalation route 121 2002
 
SANSA CORPORATION (BARBADOS) INC. (1)
6,102,036 Breath activated inhaler 154 1998
 
VAPIR, INC. (1)
6,095,153 Vaporization of volatile materials 194 1998
 
Liposome Technology, Inc. (1)
5,049,389 Novel liposome composition for the treatment of interstitial lung diseases 178 1989
 
ALLIANCE PHARMACEUTICAL CORP. (1)
* 6,041,777 Methods and apparatus for closed-circuit ventilation therapy 219 1995
 
CIVITAS THERAPEUTICS, INC. (1)
* 6,514,482 Pulmonary delivery in treating disorders of the central nervous system 153 2000
 
PENWEST PHARMACEUTICALS CO. (1)
5,738,865 Controlled release insufflation carrier for medicaments 119 1996
 
ARADIGM CORPORATION (7)
5,544,646 Systems for the intrapulmonary delivery of aerosolized aqueous formulations 204 1994
5,957,124 Dynamic particle size control for aerosolized drug delivery 175 1995
5,694,919 Lockout device for controlled release of drug from patient-activated dispenser 196 1995
5,915,378 Creating an aerosolized formulation of insulin 145 1995
5,934,272 Device and method of creating aerosolized mist of respiratory drug 242 1995
5,960,792 Device for aerosolized delivery of peptide drugs 189 1995
5,735,263 Lockout device for controlled release of drug from patient-activated dispenser 200 1996
 
NOVARTIS PHARMA AG (1)
5,758,637 Liquid dispensing apparatus and methods 211 1996
 
R. J. REYNOLDS TOBACCO COMPANY (1)
5,388,574 Aerosol delivery article 181 1993
 
Adamis Pharmaceuticals Corporation (1)
5,655,523 Dry powder inhalation device having deagglomeration/aerosolization structure responsive to patient inhalation 187 1995
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
ALEXZA PHARMACEUTICALS, INC. (52)
* 7,766,013 Aerosol generating method and device 10 2001
7,942,147 Aerosol forming device for use in inhalation therapy 6 2002
7,537,009 Method of forming an aerosol for inhalation delivery 14 2002
7,458,374 Method and apparatus for vaporizing a compound 53 2002
8,003,080 Delivery of drug amines through an inhalation route 8 2003
7,913,688 Inhalation device for producing a drug aerosol 28 2003
8,288,372 Method for treating headache with loxapine 4 2003
* 7,052,680 Delivery of compounds for the treatment of Parkinsons through an inhalation route 46 2004
* 7,011,820 Delivery of compounds for the treatment of Parkinsons through an inhalation route 47 2004
* 2004/0185,008 Delivery of compounds for the treatment of parkinsons through an inhalation route 0 2004
7,402,777 Stable initiator compositions and igniters 23 2004
* 2005/0258,159 Stable initiator compositions and igniters 34 2004
* 2004/0234,916 Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same 50 2004
7,540,286 Multiple dose condensation aerosol devices and methods of forming condensation aerosols 19 2004
7,581,540 Aerosol drug delivery device incorporating percussively activated heat packages 17 2004
7,442,368 Delivery of stimulants through an inhalation route 16 2006
7,498,019 Delivery of compounds for the treatment of headache through an inhalation route 12 2006
7,449,172 Delivery of antiemetics through an inhalation route 15 2006
7,465,435 Delivery of beta-blockers through an inhalation route 13 2006
* 7,465,436 Delivery of compounds for the treatment of Parkinson's through an inhalation route 13 2006
7,485,285 Delivery of antidepressants through an inhalation route 13 2006
7,449,173 Delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route 19 2006
7,465,437 Delivery of anti-migraine compounds through an inhalation route 13 2006
7,524,484 Delivery of diphenhydramine through an inhalation route 11 2006
7,507,398 Delivery of physiologically active compounds through an inhalation route 40 2006
* 7,449,174 Delivery of analgesics through an inhalation route 15 2006
* 7,449,175 Delivery of erectile dysfunction drugs through an inhalation route 16 2006
7,601,337 Delivery of antipsychotics through an inhalation route 9 2006
7,488,469 Delivery of caffeine through an inhalation route 13 2006
* 2006/0257,329 Delivery of drug esters through an inhalation route 48 2006
7,510,702 Delivery of nonsteroidal antiinflammatory drugs through an inhalation route 12 2006
7,470,421 Delivery of diazepam through an inhalation route 16 2006
* 7,445,768 Delivery of sedative-hypnotics through an inhalation route 17 2006
7,491,047 Delivery of antihistamines through an inhalation route 13 2006
7,507,397 Delivery of muscle relaxants through an inhalation route 13 2006
7,468,179 Delivery of opioids through an inhalation route 31 2007
7,981,401 Diuretic aerosols and methods of making and using them 5 2007
7,923,662 Stable initiator compositions and igniters 7 2008
7,988,952 Delivery of drug esters through an inhalation route 4 2008
8,235,037 Drug condensation aerosols and kits 4 2008
7,834,295 Printable igniters 6 2008
7,987,846 Method and apparatus for vaporizing a compound 4 2008
8,173,107 Delivery of antipsychotics through an inhalation route 4 2009
8,074,644 Method of forming an aerosol for inhalation delivery 5 2009
8,333,197 Multiple dose condensation aerosol devices and methods of forming condensation aerosols 3 2009
8,387,612 Self-contained heating unit and drug-supply unit employing same 4 2009
8,506,935 Respiratory drug condensation aerosols and methods of making and using them 1 2009
9,308,208 Aerosol generating method and device 0 2010
9,211,382 Drug condensation aerosols and kits 0 2012
8,991,387 Self-contained heating unit and drug-supply unit employing same 1 2013
8,955,512 Method of forming an aerosol for inhalation delivery 1 2013
9,370,629 Self-contained heating unit and drug-supply unit employing same 0 2015
 
VECTURAL LIMITED (1)
* 2010/0288,276 COMPOSITIONS FOR TREATING PARKINSON'S DISEASE 3 2008
* Cited By Examiner

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 May 9, 2016
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00