Carbohydrate derivatives of paclitaxel and docetaxel, method for producing same and uses thereof
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United States of America Patent
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Nov 9, 2004
Grant Date -
Jul 15, 2004
app pub date -
Jan 9, 2003
filing date -
Jan 9, 2003
priority date (Note) -
Expired
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Abstract
The invention relates to new carbohydrate derivatives of paclitaxel and docetaxel with increased solubility in water as compared to the parent compounds, paclitaxel and docetaxel These derivatives are produced from naturally occurring precursor molecules which upon hydrolysis yield these natural precursors and the original paclitaxel and docetaxel molecules. The present invention also relates to the composition and the use of such derivatives for cancer therapy. These derivatives may also be used in antifungal or antiviral therapy.
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