Canine and feline proteins, nucleic acid molecules and uses thereof
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United States of America Patent
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Nov 16, 2004
Grant Date -
May 2, 2002
app pub date -
Jul 27, 2001
filing date -
Aug 4, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to canine and feline proteins. In particular, the present invention discloses feline interleukin-18, feline caspase-1, feline interleukin-12 single chain and canine interleukin-12 single chain proteins. The present invention also includes feline interleukin-18, feline caspase-1, feline interleukin-12 single chain and canine interleukin-12 single chain nucleic acid molecules encoding such proteins, antibodies raised against such proteins and/or inhibitors of such proteins or nucleic acid molecules. The present invention also includes therapeutic compositions comprising such nucleic acid molecules, proteins, antibodies and/or inhibitors, as well as their use to evaluate and regulate an immune response in an animal.
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