Ketolide antibiotics
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United States of America Patent
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Dec 21, 2004
Grant Date -
Oct 24, 2002
app pub date -
Apr 5, 2002
filing date -
Jan 27, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention relates to compounds of the formula 1: ##STR1## and to pharmaceutically acceptable salts and solvates thereof wherein X.sup.1, X.sup.2, R.sup.2, R.sup.8, R.sup.9, R.sup.10 and R.sup.11 are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
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