Topical administration of basic antifungal compositions to treat fungal infections of the nails
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United States of America Patent
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Jan 25, 2005
Grant Date -
Dec 25, 2003
app pub date -
Jun 21, 2002
filing date -
Jun 21, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Methods and topical pharmaceutical formulations are provided for the treatment of nail fungus (onychomycosis). The invention involves a pharmacologically active antifungal agent, plus a pharmaceutically acceptable base in a formulation having a pH of 7.5 to about 13.0, preferably about 8.0 to 11.5, and most preferably about 8.5 to 10.5. These basic formulations permeate the nail and are effective in treating fungal infections of the nail and surrounding tissues.
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