Muteins of hypoxia inducible factor alpha and methods of use thereof
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United States of America Patent
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Feb 1, 2005
Grant Date -
Mar 6, 2003
app pub date -
Mar 19, 2002
filing date -
Mar 20, 2001
priority date (Note) -
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Abstract
The present invention provides hypoxia inducible factor alpha muteins, DNA sequences encoding these hypoxia inducible factor alpha muteins, recombinant DNA molecules containing those DNA sequences operatively linked to expression control sequences and capable of inducing expression of an hypoxia inducible factor alpha muteins, hosts transformed with those recombinant DNA molecules, pharmaceutical compositions containing hypoxia inducible factor alpha muteins and methods of using those compositions to treat hypoxia and ischemic related tissue damage.
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