Method for determining the concentration of glucose in a body fluid with glucose-containing perfusate

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United States of America Patent

PATENT NO 6852500
SERIAL NO

09620038

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Abstract

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The invention concerns a method and an arrangement for determining the concentration of glucose in a body fluid. In the microdialysis technology used for this purpose, perfusate containing glucose is transported in intermittent delivery pulses through a microdialysis probe (10) inserted into the body fluid and dialysate obtained in this process is passed to a measuring cell (16) to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the body fluid by means of a control device (18, 20) in accordance with a command variable derived from the measurement signals of the measuring cell (16). When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the body fluid.

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Patent Owner(s)

Patent OwnerAddress
ROCHE DIAGNOSTICS GMBH68305 MANNHEIM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fussgaenger, Rolf Blaustein-Weldach, DE 2 400
Gessler, Ralf Baienfurt, DE 4 661
Hoss, Udo Sherman Oaks, CA 213 10535
Pfleiderer, Hans-Joerg Ulm, DE 27 867
Zieten, Hans-Ulrich Illerrieden, DE 2 400

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