Aptamers containing sequences of nucleic acid or nucleic acid analogues bound homologously, or in novel complexes

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United States of America Patent

PATENT NO 6858390
APP PUB NO 20030022853A1
SERIAL NO

09961865

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Abstract

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An aptamer contains at least two parallel or antiparallel heteropolymeric nucleobase-containing sequences bonded together by Watson-Crick complementary base interaction or by homologous base interaction, provided that: (a) when the aptamer is single-stranded, the at least two sequences are bonded together by homologous base interaction; and (b) when the aptamer is a duplex and the at least two sequences are antiparallel to each other, the at least two sequences are bonded together by homologous base interaction. The aptamer can be used to bind ligands or to catalyze reactions when functioning as an aptazyme.

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Patent Owner(s)

Patent OwnerAddress
INGENEUS INC40A CENTRAL AMERICAN BOULEVARD C/O DELOITTE CORPORATE SERVICES BELIZE CITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Daksis, Jasmine I Richmond Hill, CA 18 135
Erikson, Glen H Providenciales, TC 23 179

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