Preparation method of biodegradable porous polymer scaffolds having an improved cell compatibility for tissue engineering

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United States of America Patent

PATENT NO 6861087
APP PUB NO 20040043135A1
SERIAL NO

10270737

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Abstract

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A method for modifying surface of biodegradable porous polymer scaffold for tissue engineering using a low temperature plasma discharge apparatus, and particularly, a method for inducing the biodegradable porous polymer scaffold to be hydrophilic by graft polymerizing a hydrophilic monomer on the surface of the biodegradable porous polymer scaffold, which is made of polylactic acid, polyglycolic acid or poly(lactic acid-glycolic acid) copolymer, using a low temperature plasma. The surface-modified porous polymer scaffold according to the present invention has an enhanced cell compatibility in cell culture in vitro, and promote tissue growth when the cell is transplanted into a body.

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Patent Owner(s)

  • KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY;SOLCO BIOMEDICAL CO., LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Kwang Duk Seoul, KR 5 45
Ahn, Saeyoung Seoul, KR 7 97
Han, Dong Keun Seoul, KR 24 290
Ju, Young Min Seoul, KR 10 104

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