Variation in drug response related to polymorphisms in the .beta.2-adrenergic receptor
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Mar 1, 2005
Grant Date -
N/A
app pub date -
May 25, 2001
filing date -
Nov 25, 1998
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A novel polymorphic site in the 5' leader cistron of the .beta..sub.2 -adrenergic receptor (.beta..sub.2 AR) gene is disclosed. The polymorphisms present at this site result in different levels of inhibition of translation of .beta..sub.2 AR mRNA. Compositions and methods for genotyping this polymorphic site as disclosed. In addition, methods for using this genotype information are disclosed, including predicting genetic predisposition to a disease modified by .beta..sub.2 AR expression and predicting a patient's bronchodilating response to .beta..sub.2 -agonists.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully