Cardiac remodeling
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United States of America Patent
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Mar 15, 2005
Grant Date -
N/A
app pub date -
Feb 11, 2000
filing date -
Feb 12, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention provides a method of treating a heart to remodel gap junctions, obtain gap junctional remodeling and/or alteration or effective refractory period comprising contacting linked multiple electrode pairs to an epicardial surface of a heart, and connecting the electrode pairs to a pacemaker to apply periodic electrical signals to the epicardial surface through the electrode pairs, the signals being applied for a sufficient time and having characteristics sufficient to remodel gap junctions, obtain gap junctional remodeling and/or alteration of effective refractory period in the heart. The invention also provides a device comprising a strip of electrode material having mounted thereon linked multiple electrode pairs arranged in two columns.
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