Dibenzosuberanyl piperazine derivatives and drug-resistance overcoming agents containing the derivatives
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United States of America Patent
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Apr 19, 2005
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N/A
app pub date -
May 22, 2003
filing date -
Nov 22, 2000
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Expired
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Abstract
Dibenzosuberanyl piperazine derivatives represented by the following formula (I): ##STR1## wherein R represents an aliphatic hydrocarbon group, which may contain one or more heteroatom-containing substituent groups and may preferably contain 2 to 30 carbon atoms, and physiologically acceptable salts thereof; and medicinal compositions containing these dibenzosuberanyl piperazine derivatives and/or physiologically acceptable salts thereof. These compounds show effectiveness in allowing resistance-acquired causes of diseases to restore sensitivity to drug, that is, a resistance overcoming effect.
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