Antitumoral composition based on immunogenic polypeptide with modified cell location
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United States of America Patent
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Apr 26, 2005
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N/A
app pub date -
Apr 17, 2000
filing date -
Jul 18, 1997
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Abstract
Antitumoral compositions can comprise as therapeutic agent one or several immunogenic polypeptides, of which at least one is modified so as to have a cell location different from its native location. Compositions can be based on a recombinant vector expressing such an immunogenic polypeptide. A recombinant vector comprising at least the sequences coding for an immunogenic polypeptide originating from a precocious and/or tardive region of a papillomavirus having a modified location and a viral particle comprising the vector is also described. Finally, therapeutic uses of such a composition, such a recombinant vector and such a viral particle are described.
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