US Patent No: 6,885,889

Number of patents in Portfolio can not be more than 2000

Method and apparatus for optimizing cardiac resynchronization therapy based on left ventricular acceleration

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ALSO PUBLISHED AS: 20040172079
ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

A system and method for monitoring left ventricular cardiac contractility and for optimizing a cardiac therapy based on left ventricular lateral wall acceleration (LVA) are provided. The system includes an implantable or external cardiac stimulation device in association with a set of leads including a left ventricular epicardial or coronary sinus lead equipped with an acceleration sensor. The device receives and processes acceleration sensor signals to determine a signal characteristic indicative of LVA during isovolumic contraction. A therapy optimization method evaluates the LVA during varying therapy settings and selects the setting(s) that correspond to a maximum LVA during isovolumic contraction. In one embodiment, the optimal inter-ventricular pacing interval for use in cardiac resynchronization therapy is determined as the interval corresponding to the highest amplitude of the first LVA peak during isovolumic contraction.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MEDTRONIC, INC.MINNEAPOLIS, MN4949

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chinchoy, Edward Golden Valley, MN 27 191

Cited Art

Patent Info (Count) # Cites Year
 
PACESETTER, INC. (4)
5,628,777 Implantable leads incorporating cardiac wall acceleration sensors and method of fabrication 99 1993
5,549,652 Cardiac wall motion-based automatic capture verification system and method 37 1993
5,549,650 System and method for providing hemodynamically optimal pacing therapy 120 1994
6,473,645 System and method for programmably controlling electrode activation sequence in a multi-site cardiac stimulation device 37 2001
 
CARDIAC PACEMAKERS, INC. (2)
5,540,727 Method and apparatus to automatically optimize the pacing mode and pacing cycle parameters of a dual chamber pacemaker 246 1994
5,836,987 Apparatus and method for optimizing cardiac performance by determining the optimal timing interval from an accelerometer signal 236 1997
 
MEDTRONIC, INC. (2)
6,070,101 Multiple channel, sequential, cardiac pacing systems 103 1999
6,223,082 Four-chamber pacing system for optimizing cardic output and determining heart condition 107 2000
 
SORIN BIOMEDICA S.P.A. (2)
5,454,838 Method and a device for monitoring heart function 77 1993
5,693,075 Device for determining myocardial function and corresponding procedure 62 1996
 
BOZIDAR FEREK-PETRIC SOVINEC 17 (1)
5,261,418 Cardiac lead with tensiometric element for providing signals corresponding to heart contractions 27 1991
 
SULZER INTERMEDICS INC. (1)
5,941,904 Electromagnetic acceleration transducer for implantable medical device 98 1997
 
Other [Check patent profile for assignment information] (1)
6,077,236 Apparatus for monitoring cardiac contractility 25 1996

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
CARDIAC PACEMAKERS, INC. (26)
7,127,289 Cardiac resynchronization system employing mechanical measurement of cardiac walls 9 2001
7,972,275 Method and apparatus for monitoring of diastolic hemodynamics 1 2002
7,209,786 Method and apparatus for optimization of cardiac resynchronization therapy using heart sounds 24 2004
8,271,093 Systems and methods for deriving relative physiologic measurements using a backend computing system 0 2004
7,662,104 Method for correction of posture dependence on heart sounds 9 2005
7,386,345 Apparatus and method for temporary treatment of acute heart failure decompensation 0 2005
7,424,321 Systems and methods for multi-axis cardiac vibration measurements 14 2005
7,922,669 Ischemia detection using a heart sound sensor 8 2005
7,742,815 Using implanted sensors for feedback control of implanted medical devices 3 2005
7,440,803 Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 5 2005
8,108,034 Systems and methods for valvular regurgitation detection 3 2005
8,000,780 Detection of myocardial ischemia from the time sequence of implanted sensor measurements 2 2006
7,904,155 Cardiac resynchronization method and apparatus employing mechanical measurement of cardiac walls 2 2006
7,953,484 Method and apparatus for optimization of cardiac resynchronization therapy using heart sounds 0 2007
7,844,330 Dynamic device therapy control for treating post myocardial infarction patients 2 2007
7,840,267 Closed-loop resynchronization therapy for mechanical dyssynchrony 0 2007
7,844,334 Dual-use sensor for rate responsive pacing and heart sound monitoring 5 2007
7,955,268 Multiple sensor deployment 0 2007
8,126,548 Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 1 2008
8,295,927 Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 0 2008
8,369,960 Systems and methods for controlling wireless signal transfers between ultrasound-enabled medical devices 0 2009
7,899,532 Method and apparatus for minimizing post-infarct ventricular remodeling 0 2009
8,034,000 Ischemia detection using a heart sound sensor 2 2009
7,951,087 Method for correction of posture dependence on heart sounds 0 2009
7,949,394 Using implanted sensors for feedback control of implanted medical devices 0 2010
7,938,781 Hemodynamic stability assessment based on heart sounds 2 2010
 
MEDTRONIC, INC. (8)
7,610,088 Method and apparatus for assessing left ventricular function and optimizing cardiac pacing intervals based on left ventricular wall motion 3 2003
7,715,917 Method and apparatus for determining an efficacious atrioventricular delay interval 4 2004
7,769,451 Method and apparatus for optimizing cardiac resynchronization therapy 0 2005
7,653,437 Method and apparatus for determining optimal pacing therapy timing intervals 0 2006
7,877,144 Predicting chronic optimal A-V intervals for biventricular pacing via observed inter-atrial delay 0 2006
7,930,027 Method and apparatus to deliver mechanically fused pacing therapy 3 2007
8,150,513 Method and apparatus for assessing left ventricular function and optimizing cardiac pacing intervals based on left ventricular wall motion 0 2009
8,355,784 Dynamic representation of multipolar leads in a programmer interface 0 2011
 
PACESETTER, INC. (6)
7,787,951 System and method for determining optimal stimulation sites based on ECG information 1 2006
7,630,767 System and method for communicating information using encoded pacing pulses within an implantable medical system 6 2006
8,388,670 Sensor/lead systems for use with implantable medical devices 0 2007
8,155,756 Motion-based optimization for placement of cardiac stimulation electrodes 1 2009
8,195,292 Cardiac resynchronization therapy optimization using parameter estimation from realtime electrode motion tracking 0 2009
8,346,372 Motion-based optimization for placement of cardiac stimulation electrodes 0 2012
 
REMON MEDICAL TECHNOLOGIES LTD. (4)
7,621,905 Devices for intrabody delivery of molecules and systems and methods utilizing same 9 2003
7,813,808 Implanted sensor system with optimized operational and sensing parameters 0 2005
7,641,619 Barometric pressure correction based on remote sources of information 5 2007
7,948,148 Piezoelectric transducer 1 2009
 
PROTEUS DIGITAL HEALTH, INC. (3)
8,036,743 Automated optimization of multi-electrode pacing for cardiac resynchronization 0 2006
7,983,751 Measuring conduction velocity using one or more satellite devices 0 2006
8,412,347 Methods and apparatus for leads for implantable devices 0 2009
 
CARDIOSYNC, INC. (1)
8,118,751 Devices and methods for accelerometer-based characterization of cardiac function and identification of LV target pacing zones 0 2009
 
COORDENACAO DE APERFEICOAMENTO DE PESSOAL DE NIVEL SUPERIOR (CAPES) (1)
8,280,136 Method and apparatus for detecting intraventricular dyssynchrony 0 2006
 
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (1)
8,131,043 Method and apparatus for detecting interventricular dyssynchrony 2 2006

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