Inhibition of angiogenesis in disease states with an anti-αvβ3 monoclonal antibody

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United States of America Patent

PATENT NO 6887473
SERIAL NO

09081522

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Abstract

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The present invention describes methods for inhibition angiogenesis in tissues using vitronectin αvβ3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic compositions containing αvβ3 antagonists.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL INSTITUTES OF HEALTH THE6701 ROCKLEDGE DRIVE ROOM 3188 MSC 7750 THE EXTRAMURAL INVENTIONS OFFICE BETHESDA MD 20892

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brooks, Peter West Harrison, NY 40 472
Cheresh, David A Encinitas, CA 35 334

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