Compositions and methods for producing vascular occlusion
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United States of America Patent
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May 3, 2005
Issued Date -
N/A
app pub date -
Nov 12, 1999
filing date -
Nov 12, 1998
priority date (Note) -
Expired
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Abstract
The present invention relates generally to methods and compositions for targeting, delivering, and activating platelet-dependent vascular occlusion agents. In particular, antibodies carrying platelet binding agents are targeted to hyperplastic cells or tissues, such as the vasculature of solid tumor masses; the platelet binding agent then binds and activates platelets, which in turn bind and activate other platelets. This process results in the formation of a platelet-mediated thrombus-causing vessel occlusion.
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