Hydrolyzable delivery system using cross-linked polymeric resins as vehicles
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United States of America Patent
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May 10, 2005
Grant Date -
N/A
app pub date -
Mar 30, 1998
filing date -
Apr 4, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention provides a method of preparing a polymeric delivery system for active ingredients. The delivery system is formed either by attaching the active ingredient to a linker through a hydrolyzable covalent bond, then forming a covalent bond between the linker and a portion of the subunits of a cross-linked polymer, or by attaching a linker to a portion of the subunits of a cross-linked polymer, then attaching the active ingredient to the polymer-linker combination through a hydrolyzable covalent bond. The invention also provides a delivery system comprising an active ingredient covalently bonded through a hydrolyzale covalent bond to a linker, which is in turn covalently bonded to a portion of subunits of a cross-linked polymer.
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