Particle delivery techniques
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United States of America Patent
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May 17, 2005
Issued Date -
N/A
app pub date -
Dec 17, 1998
filing date -
Jun 17, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method is provided for in vivo or ex vivo delivery of a preparation of powdered nucleic acid molecules into vertebrate tissue for transformation of cells in the tissue using needleless injection techniques. The method can be used to deliver therapeutically relevant nucleotide sequences to cells in mammalian tissue to provide gene therapy, elicit immunity or to provide antisense or ribozyme functions. A method for providing densified processed pharmaceutical compositions is also described. The method is used to convert non-dense pharmaceutical powders or particulate formulations into densified particles optimally suited for transdermal delivery using a needleless syringe. The method is also used to optimize the density and particle size of powders and particulate formulations for subsequent transdermal delivery thereof. Densified pharmaceutical compositions formed by the present methods are also provided.
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
| Patent Owner | Address | |
|---|---|---|
| POWDERJECT RESEARCH LIMITED | 4 ROBERT ROBINSON AVENUE THE OXFORD SCIENCE PARK OXFORD QX4 4GA |
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Inventor(s)
| Inventor Name | Address | # of filed Patents | Total Citations |
|---|---|---|---|
| Burkoth, Terry Lee | Palo Alto, CA | 5 | 237 |
| Muddle, Andrew Gordon | Cambs, GB | 2 | 57 |
| Porter, Linda Maree | The Gap, AU | 2 | 57 |
| Sarphie, David Francis | Madison, WI | 5 | 231 |
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| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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