Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
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United States of America Patent
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Jul 19, 2005
Grant Date -
Nov 6, 2003
app pub date -
Nov 20, 2001
filing date -
Nov 28, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention concerns paclitaxel solubilizers and formulations thereof with a high propensity to dissolve paclitaxel. The formulations of the invention reduce or obviate the need for the disadvantageous excipient Cremophor® EL. The formulations of the invention are useful for administering paclitaxel, its derivatives, or pharmaceutically acceptable salts or such derivatives to patients in need thereof. The formulations of the invention are suitable for parenteral, oral, local, or transdermal administration to mammals including humans, particularly for intravenous delivery.
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