Processes for producing polymer coatings for release of therapeutic agent
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United States of America Patent
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Aug 2, 2005
Grant Date -
Nov 11, 2004
app pub date -
May 6, 2003
filing date -
May 6, 2003
priority date (Note) -
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Abstract
A method for furnishing a therapeutic-agent-containing medical device is provided. The method comprises: (a) providing a reactive layer comprising a cross-linking agent on a medical device surface; and (b) subsequently applying a polymer-containing layer, which comprises a polymer and a therapeutic agent, over the reactive layer. The cross-linking agent interacts with the polymer to form a cross-linked polymeric region that comprises the therapeutic agent. Examples of medical devices include implantable or insertable medical devices, for example, catheters, balloon, cerebral aneurysm filler coils, arterio-venous shunts and stents.
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