Macrolide analogs

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United States of America Patent

PATENT NO 6927057
APP PUB NO 20020068332A1
SERIAL NO

09859854

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Abstract

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Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.

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Patent Owner(s)

Patent OwnerAddress
KOSAN BIOSCIENCES3832 BAY CENTER PLACE HAYWARD CA 94545

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ashley, Gary Alameda, CA 55 477
Kao, Camilla M Palo Alto, CA 14 26
Khosla, Chaitan Palo Alto, CA 123 1815
McDaniel, Robert Palo Alto, CA 77 881

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