Modified dendritic cells and use therefor
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Aug 16, 2005
Grant Date -
N/A
app pub date -
Mar 31, 2000
filing date -
Apr 1, 1999
priority date (Note) -
Expired
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Abstract
The invention provides isolated dendritic cells genetically modified to express a selectin polypeptide, optionally treated with activated platelets or membrane microparticles thereof. The invention also provides isolated platelet modified dendritic cells. Methods for delivering the modified dendritic cells to peripheral lymph nodes and methods for using the modified dendritic cells to stimulate immune responses also are provided. Vaccine compositions containing the modified dendritic cells also are provided.
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