Method for immobilizing multistranded nucleic acid molecules by modifying more than one strand thereof, and binding each strand to a solid support
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United States of America Patent
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Aug 30, 2005
Grant Date -
May 22, 2003
app pub date -
Jul 31, 2002
filing date -
Jul 31, 2001
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Abstract
Various methodologies for the immobilization of molecules such, as multistranded nucleic acid molecules, are described. The methodologies include activation of solid supports, as well as treatment of, e.g. termini of nucleic acid molecules to render them more receptive to immobilization on surfaces.
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